Treatment of Aggressive Antineutrophil Cytoplasmic Antibody–Associated Vasculitis With Eculizumab

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Treatment of antineutrophil cytoplasmic antibody-associated vasculitis.

PURPOSE OF REVIEW The primary idiopathic small-vessel vasculitis syndromes include granulomatosis with polyangiitis, Churg-Strauss syndrome, and microscopic polyangiitis. These disorders are commonly referred to as antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides and prominently affect the pulmonary vasculature. Although significant progress has been made in the management of ...

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Antineutrophil Cytoplasmic Antibody Vasculitis Associated with Influenza Vaccination

Background: Administration of influenza vaccines has been associated with the development of autoantibodies and autoimmune rheumatic disease. Patients: We discuss 2 patients who developed antineutrophil cytoplasmic antibody-associated vasculitis (AAV) in temporal association with influenza immunization. AAV was diagnosed 2 and 4 weeks after immunization in these patients. Both patients had rena...

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HLA-B52-positive Aortitis with Antineutrophil Cytoplasmic Antibody-associated Vasculitis

A 73-year-old man presented with a 1-month history of fever and numbness of the bilateral upper and lower extremities. Laboratory tests showed positive myeloperoxidaseantineutrophil cytoplasmic antibody (ANCA) results (296 U/ mL). Computed tomography (CT) showed wall thickening in the thoracic aorta and common carotid arteries (Picture A), and gallium single-photon emission CT/CT showed accumul...

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Antineutrophil cytoplasmic antibody vasculitis associated with influenza vaccination.

BACKGROUND Administration of influenza vaccines has been associated with the development of autoantibodies and autoimmune rheumatic disease. PATIENTS We discuss 2 patients who developed antineutrophil cytoplasmic antibody-associated vasculitis (AAV) in temporal association with influenza immunization. AAV was diagnosed 2 and 4 weeks after immunization in these patients. Both patients had rena...

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Two cases of systemic antineutrophil cytoplasmic antibody (ANCA) vasculitis in the setting of chronic lymphocytic leukaemia and angioimmunoblastic lymphadenopathy type T cell lymphoma are reported. The two patients had fever of unknown origin associated with cutaneous vasculitis and "pulmonary-renal syndrome" with alveolar haemorrhage. Despite anti-infectious treatments, steroids, and chemother...

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ژورنال

عنوان ژورنال: Kidney International Reports

سال: 2020

ISSN: 2468-0249

DOI: 10.1016/j.ekir.2019.11.021